The structural variability of the influenza A hemagglutinin receptor-binding site
Identifieur interne : 000260 ( Main/Exploration ); précédent : 000259; suivant : 000261The structural variability of the influenza A hemagglutinin receptor-binding site
Auteurs : Michal Lazniewski [Pologne] ; Wayne K. Dawson [Pologne] ; Teresa Szczepi Ska [Pologne] ; Dariusz Plewczynski [Pologne]Source :
- Briefings in Functional Genomics [ 2041-2649 ] ; 2017.
Abstract
Hemagglutinin (HA) is a transmembrane protein of the influenza A virus and a key component in its life cycle. The protein allows the virus to enter a host cell by recognizing specific glycans attached to transmembrane proteins of the host, which leads to viral endocytosis. In recent years, significant progress has been made in understanding the structural relationship between changes in the HA receptor-binding site (RBS) and the sialylated glycans that bind them. Several mutations were identified in the HA RBS that allows the virus to change host tropism. Their impact on binding the analogs of human and avian receptors was determined with X-ray crystallography. In this article, we provide a short overview of the HA protein structure and briefly discuss the adaptive mutations introduced to different HA subtypes.
Url:
DOI: 10.1093/bfgp/elx042
PubMed: 29253080
PubMed Central: 6252403
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000932
- to stream Pmc, to step Curation: 000932
- to stream Pmc, to step Checkpoint: 000185
- to stream Ncbi, to step Merge: 000E39
- to stream Ncbi, to step Curation: 000E39
- to stream Ncbi, to step Checkpoint: 000E39
- to stream Main, to step Merge: 000260
- to stream Main, to step Curation: 000260
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The structural variability of the influenza A hemagglutinin receptor-binding site</title><author><name sortKey="Lazniewski, Michal" sort="Lazniewski, Michal" uniqKey="Lazniewski M" first="Michal" last="Lazniewski">Michal Lazniewski</name><affiliation wicri:level="1"><nlm:aff id="aff1">University of Warsaw, Center of New Technologies (CeNT), Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>University of Warsaw, Center of New Technologies (CeNT), Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Physical Chemistry in the Faculty of Pharmacy at the Medical University of Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Physical Chemistry in the Faculty of Pharmacy at the Medical University of Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Dawson, Wayne K" sort="Dawson, Wayne K" uniqKey="Dawson W" first="Wayne K" last="Dawson">Wayne K. Dawson</name><affiliation wicri:level="1"><nlm:aff id="aff1">University of Warsaw, Center of New Technologies (CeNT), Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>University of Warsaw, Center of New Technologies (CeNT), Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation><affiliation><nlm:aff id="aff3">Bio-information Lab in Yayoi campus at the University of Tokyo</nlm:aff></affiliation></author><author><name sortKey="Szczepi Ska, Teresa" sort="Szczepi Ska, Teresa" uniqKey="Szczepi Ska T" first="Teresa" last="Szczepi Ska">Teresa Szczepi Ska</name><affiliation wicri:level="1"><nlm:aff id="aff4">Professor Dariusz Plewczyński Laboratory at Center of New Technologies, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Professor Dariusz Plewczyński Laboratory at Center of New Technologies, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Plewczynski, Dariusz" sort="Plewczynski, Dariusz" uniqKey="Plewczynski D" first="Dariusz" last="Plewczynski">Dariusz Plewczynski</name><affiliation wicri:level="1"><nlm:aff id="aff1">University of Warsaw, Center of New Technologies (CeNT), Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>University of Warsaw, Center of New Technologies (CeNT), Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">29253080</idno><idno type="pmc">6252403</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252403</idno><idno type="RBID">PMC:6252403</idno><idno type="doi">10.1093/bfgp/elx042</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">000932</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000932</idno><idno type="wicri:Area/Pmc/Curation">000932</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000932</idno><idno type="wicri:Area/Pmc/Checkpoint">000185</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000185</idno><idno type="wicri:Area/Ncbi/Merge">000E39</idno><idno type="wicri:Area/Ncbi/Curation">000E39</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E39</idno><idno type="wicri:doubleKey">2041-2649:2017:Lazniewski M:the:structural:variability</idno><idno type="wicri:Area/Main/Merge">000260</idno><idno type="wicri:Area/Main/Curation">000260</idno><idno type="wicri:Area/Main/Exploration">000260</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The structural variability of the influenza A hemagglutinin receptor-binding site</title><author><name sortKey="Lazniewski, Michal" sort="Lazniewski, Michal" uniqKey="Lazniewski M" first="Michal" last="Lazniewski">Michal Lazniewski</name><affiliation wicri:level="1"><nlm:aff id="aff1">University of Warsaw, Center of New Technologies (CeNT), Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>University of Warsaw, Center of New Technologies (CeNT), Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Physical Chemistry in the Faculty of Pharmacy at the Medical University of Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Physical Chemistry in the Faculty of Pharmacy at the Medical University of Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Dawson, Wayne K" sort="Dawson, Wayne K" uniqKey="Dawson W" first="Wayne K" last="Dawson">Wayne K. Dawson</name><affiliation wicri:level="1"><nlm:aff id="aff1">University of Warsaw, Center of New Technologies (CeNT), Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>University of Warsaw, Center of New Technologies (CeNT), Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation><affiliation><nlm:aff id="aff3">Bio-information Lab in Yayoi campus at the University of Tokyo</nlm:aff></affiliation></author><author><name sortKey="Szczepi Ska, Teresa" sort="Szczepi Ska, Teresa" uniqKey="Szczepi Ska T" first="Teresa" last="Szczepi Ska">Teresa Szczepi Ska</name><affiliation wicri:level="1"><nlm:aff id="aff4">Professor Dariusz Plewczyński Laboratory at Center of New Technologies, Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Professor Dariusz Plewczyński Laboratory at Center of New Technologies, Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author><author><name sortKey="Plewczynski, Dariusz" sort="Plewczynski, Dariusz" uniqKey="Plewczynski D" first="Dariusz" last="Plewczynski">Dariusz Plewczynski</name><affiliation wicri:level="1"><nlm:aff id="aff1">University of Warsaw, Center of New Technologies (CeNT), Warsaw, Poland</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>University of Warsaw, Center of New Technologies (CeNT), Warsaw</wicri:regionArea><wicri:noRegion>Warsaw</wicri:noRegion></affiliation></author></analytic><series><title level="j">Briefings in Functional Genomics</title><idno type="ISSN">2041-2649</idno><idno type="eISSN">2041-2657</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>Hemagglutinin (HA) is a transmembrane protein of the influenza A virus and a key component in its life cycle. The protein allows the virus to enter a host cell by recognizing specific glycans attached to transmembrane proteins of the host, which leads to viral endocytosis. In recent years, significant progress has been made in understanding the structural relationship between changes in the HA receptor-binding site (RBS) and the sialylated glycans that bind them. Several mutations were identified in the HA RBS that allows the virus to change host tropism. Their impact on binding the analogs of human and avian receptors was determined with X-ray crystallography. In this article, we provide a short overview of the HA protein structure and briefly discuss the adaptive mutations introduced to different HA subtypes.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Webster, Rg" uniqKey="Webster R">RG Webster</name></author><author><name sortKey="Bean, Wj" uniqKey="Bean W">WJ Bean</name></author><author><name sortKey="Gorman, Ot" uniqKey="Gorman O">OT. Gorman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y Wu</name></author><author><name sortKey="Tefsen, B" uniqKey="Tefsen B">B Tefsen</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamayoshi, S" uniqKey="Yamayoshi S">S Yamayoshi</name></author><author><name sortKey="Watanabe, M" uniqKey="Watanabe M">M Watanabe</name></author><author><name sortKey="Goto, H" uniqKey="Goto H">H Goto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jagger, Bw" uniqKey="Jagger B">BW Jagger</name></author><author><name sortKey="Wise, Hm" uniqKey="Wise H">HM Wise</name></author><author><name sortKey="Kash, Jc" uniqKey="Kash J">JC Kash</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kr L, E" uniqKey="Kr L E">E Król</name></author><author><name sortKey="Rychlowska, M" uniqKey="Rychlowska M">M Rychłowska</name></author><author><name sortKey="Szewczyk, B" uniqKey="Szewczyk B">B. Szewczyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Graaf, M" uniqKey="De Graaf M">M de Graaf</name></author><author><name sortKey="Fouchier, Ra" uniqKey="Fouchier R">RA. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tzarum, N" uniqKey="Tzarum N">N Tzarum</name></author><author><name sortKey="De Vries, Rp" uniqKey="De Vries R">RP de Vries</name></author><author><name sortKey="Peng, W" uniqKey="Peng W">W Peng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Matrosovich, M" uniqKey="Matrosovich M">M Matrosovich</name></author><author><name sortKey="Stech, J" uniqKey="Stech J">J Stech</name></author><author><name sortKey="Klenk, Hd" uniqKey="Klenk H">HD. Klenk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zambon, M" uniqKey="Zambon M">M. Zambon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miotto, O" uniqKey="Miotto O">O Miotto</name></author><author><name sortKey="Heiny, At" uniqKey="Heiny A">AT Heiny</name></author><author><name sortKey="Albrecht, R" uniqKey="Albrecht R">R Albrecht</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Yp" uniqKey="Lin Y">YP Lin</name></author><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Wharton, Sa" uniqKey="Wharton S">SA Wharton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neumann, G" uniqKey="Neumann G">G Neumann</name></author><author><name sortKey="Noda, T" uniqKey="Noda T">T Noda</name></author><author><name sortKey="Kawaoka, Y" uniqKey="Kawaoka Y">Y. Kawaoka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, R" uniqKey="Xu R">R Xu</name></author><author><name sortKey="Mcbride, R" uniqKey="Mcbride R">R McBride</name></author><author><name sortKey="Nycholat, Cm" uniqKey="Nycholat C">CM Nycholat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Girard, Mp" uniqKey="Girard M">MP Girard</name></author><author><name sortKey="Tam, Js" uniqKey="Tam J">JS Tam</name></author><author><name sortKey="Assossou, Om" uniqKey="Assossou O">OM Assossou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Gj" uniqKey="Smith G">GJ Smith</name></author><author><name sortKey="Vijaykrishna, D" uniqKey="Vijaykrishna D">D Vijaykrishna</name></author><author><name sortKey="Bahl, J" uniqKey="Bahl J">J Bahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wei, Sh" uniqKey="Wei S">SH Wei</name></author><author><name sortKey="Yang, Jr" uniqKey="Yang J">JR Yang</name></author><author><name sortKey="Wu, Hs" uniqKey="Wu H">HS Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, H" uniqKey="Yang H">H Yang</name></author><author><name sortKey="Carney, Pj" uniqKey="Carney P">PJ Carney</name></author><author><name sortKey="Donis, Ro" uniqKey="Donis R">RO Donis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puzelli, S" uniqKey="Puzelli S">S Puzelli</name></author><author><name sortKey="Rossini, G" uniqKey="Rossini G">G Rossini</name></author><author><name sortKey="Facchini, M" uniqKey="Facchini M">M Facchini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y Huang</name></author><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kilbourne, Ed" uniqKey="Kilbourne E">ED. Kilbourne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Das, K" uniqKey="Das K">K Das</name></author><author><name sortKey="Aramini, Jm" uniqKey="Aramini J">JM Aramini</name></author><author><name sortKey="Ma, Lc" uniqKey="Ma L">LC Ma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kadam, Ru" uniqKey="Kadam R">RU Kadam</name></author><author><name sortKey="Wilson, Ia" uniqKey="Wilson I">IA. Wilson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Russell, Rj" uniqKey="Russell R">RJ Russell</name></author><author><name sortKey="Kerry, Ps" uniqKey="Kerry P">PS Kerry</name></author><author><name sortKey="Stevens, Dj" uniqKey="Stevens D">DJ Stevens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, X" uniqKey="Wu X">X Wu</name></author><author><name sortKey="Sun, Q" uniqKey="Sun Q">Q Sun</name></author><author><name sortKey="Zhang, C" uniqKey="Zhang C">C Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eng, Cl" uniqKey="Eng C">CL Eng</name></author><author><name sortKey="Tong, Jc" uniqKey="Tong J">JC Tong</name></author><author><name sortKey="Tan, Tw" uniqKey="Tan T">TW. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eng, Clp" uniqKey="Eng C">CLP Eng</name></author><author><name sortKey="Tong, Jc" uniqKey="Tong J">JC Tong</name></author><author><name sortKey="Tan, Tw" uniqKey="Tan T">TW Tan</name></author><author><name sortKey="Chan, Mcw" uniqKey="Chan M">MCW. Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harrison, Sc" uniqKey="Harrison S">SC. Harrison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carr, Cm" uniqKey="Carr C">CM Carr</name></author><author><name sortKey="Chaudhry, C" uniqKey="Chaudhry C">C Chaudhry</name></author><author><name sortKey="Kim, Ps" uniqKey="Kim P">PS. Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="White, Jm" uniqKey="White J">JM White</name></author><author><name sortKey="Whittaker, Gr" uniqKey="Whittaker G">GR. Whittaker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smrt, St" uniqKey="Smrt S">ST Smrt</name></author><author><name sortKey="Lorieau, Jl" uniqKey="Lorieau J">JL. Lorieau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Worch, R" uniqKey="Worch R">R. Worch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Worch, R" uniqKey="Worch R">R Worch</name></author><author><name sortKey="Krupa, J" uniqKey="Krupa J">J Krupa</name></author><author><name sortKey="Filipek, A" uniqKey="Filipek A">A Filipek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gamblin, Sj" uniqKey="Gamblin S">SJ Gamblin</name></author><author><name sortKey="Skehel, Jj" uniqKey="Skehel J">JJ. Skehel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ma, W" uniqKey="Ma W">W Ma</name></author><author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A Garcia-Sastre</name></author><author><name sortKey="Schwemmle, M" uniqKey="Schwemmle M">M. Schwemmle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Mccauley, Jw" uniqKey="Mccauley J">JW McCauley</name></author><author><name sortKey="Steinhauer, Da" uniqKey="Steinhauer D">DA. Steinhauer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, Ia" uniqKey="Wilson I">IA Wilson</name></author><author><name sortKey="Skehel, Jj" uniqKey="Skehel J">JJ Skehel</name></author><author><name sortKey="Wiley, Dc" uniqKey="Wiley D">DC. Wiley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Aevermann, Bd" uniqKey="Aevermann B">BD Aevermann</name></author><author><name sortKey="Anderson, Tk" uniqKey="Anderson T">TK Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mazzocco, G" uniqKey="Mazzocco G">G Mazzocco</name></author><author><name sortKey="Lazniewski, M" uniqKey="Lazniewski M">M Lazniewski</name></author><author><name sortKey="Migdal, P" uniqKey="Migdal P">P Migdał</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ambroggio, Xi" uniqKey="Ambroggio X">XI Ambroggio</name></author><author><name sortKey="Dommer, J" uniqKey="Dommer J">J Dommer</name></author><author><name sortKey="Gopalan, V" uniqKey="Gopalan V">V Gopalan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicholls, Jm" uniqKey="Nicholls J">JM Nicholls</name></author><author><name sortKey="Chan, Rw" uniqKey="Chan R">RW Chan</name></author><author><name sortKey="Russell, Rj" uniqKey="Russell R">RJ Russell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Walther, T" uniqKey="Walther T">T Walther</name></author><author><name sortKey="Karamanska, R" uniqKey="Karamanska R">R Karamanska</name></author><author><name sortKey="Chan, Rw" uniqKey="Chan R">RW Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Franca, M" uniqKey="Franca M">M Franca</name></author><author><name sortKey="Stallknecht, De" uniqKey="Stallknecht D">DE Stallknecht</name></author><author><name sortKey="Howerth, Ew" uniqKey="Howerth E">EW. Howerth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Xiao, H" uniqKey="Xiao H">H Xiao</name></author><author><name sortKey="Martin, Sr" uniqKey="Martin S">SR Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stray, Sj" uniqKey="Stray S">SJ Stray</name></author><author><name sortKey="Cummings, Rd" uniqKey="Cummings R">RD Cummings</name></author><author><name sortKey="Air, Gm" uniqKey="Air G">GM. Air</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arcanjo, Ac" uniqKey="Arcanjo A">AC Arcanjo</name></author><author><name sortKey="Mazzocco, G" uniqKey="Mazzocco G">G Mazzocco</name></author><author><name sortKey="De Oliveira, Sf" uniqKey="De Oliveira S">SF de Oliveira</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, N" uniqKey="Zhao N">N Zhao</name></author><author><name sortKey="Martin, Be" uniqKey="Martin B">BE Martin</name></author><author><name sortKey="Yang, Ck" uniqKey="Yang C">CK Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murphy, Br" uniqKey="Murphy B">BR Murphy</name></author><author><name sortKey="Wood, Ft" uniqKey="Wood F">FT Wood</name></author><author><name sortKey="Massicot, Jg" uniqKey="Massicot J">JG Massicot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baum, Lg" uniqKey="Baum L">LG Baum</name></author><author><name sortKey="Paulson, Jc" uniqKey="Paulson J">JC. Paulson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ginting, Te" uniqKey="Ginting T">TE Ginting</name></author><author><name sortKey="Shinya, K" uniqKey="Shinya K">K Shinya</name></author><author><name sortKey="Kyan, Y" uniqKey="Kyan Y">Y Kyan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Byrd Leotis, L" uniqKey="Byrd Leotis L">L Byrd-Leotis</name></author><author><name sortKey="Cummings, Rd" uniqKey="Cummings R">RD Cummings</name></author><author><name sortKey="Steinhauer, Da" uniqKey="Steinhauer D">DA. Steinhauer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ni, F" uniqKey="Ni F">F Ni</name></author><author><name sortKey="Kondrashkina, E" uniqKey="Kondrashkina E">E Kondrashkina</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kash, Jc" uniqKey="Kash J">JC Kash</name></author><author><name sortKey="Taubenberger, Jk" uniqKey="Taubenberger J">JK. Taubenberger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gamblin, Sj" uniqKey="Gamblin S">SJ Gamblin</name></author><author><name sortKey="Haire, Lf" uniqKey="Haire L">LF Haire</name></author><author><name sortKey="Russell, Rj" uniqKey="Russell R">RJ Russell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, H" uniqKey="Yang H">H Yang</name></author><author><name sortKey="Carney, P" uniqKey="Carney P">P Carney</name></author><author><name sortKey="Stevens, J" uniqKey="Stevens J">J. Stevens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pappas, C" uniqKey="Pappas C">C Pappas</name></author><author><name sortKey="Yang, H" uniqKey="Yang H">H Yang</name></author><author><name sortKey="Carney, Pj" uniqKey="Carney P">PJ Carney</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Stevens, Dj" uniqKey="Stevens D">DJ Stevens</name></author><author><name sortKey="Haire, Lf" uniqKey="Haire L">LF Haire</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ha, Y" uniqKey="Ha Y">Y Ha</name></author><author><name sortKey="Stevens, Dj" uniqKey="Stevens D">DJ Stevens</name></author><author><name sortKey="Skehel, Jj" uniqKey="Skehel J">JJ Skehel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weis, Wi" uniqKey="Weis W">WI Weis</name></author><author><name sortKey="Brunger, At" uniqKey="Brunger A">AT Brunger</name></author><author><name sortKey="Skehel, Jj" uniqKey="Skehel J">JJ Skehel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, X" uniqKey="Zhu X">X Zhu</name></author><author><name sortKey="Viswanathan, K" uniqKey="Viswanathan K">K Viswanathan</name></author><author><name sortKey="Raman, R" uniqKey="Raman R">R Raman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stevens, J" uniqKey="Stevens J">J Stevens</name></author><author><name sortKey="Blixt, O" uniqKey="Blixt O">O Blixt</name></author><author><name sortKey="Paulson, Jc" uniqKey="Paulson J">JC Paulson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Vries, Rp" uniqKey="De Vries R">RP de Vries</name></author><author><name sortKey="Zhu, X" uniqKey="Zhu X">X Zhu</name></author><author><name sortKey="Mcbride, R" uniqKey="Mcbride R">R McBride</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Coombs, Pj" uniqKey="Coombs P">PJ Coombs</name></author><author><name sortKey="Martin, Sr" uniqKey="Martin S">SR Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Imai, M" uniqKey="Imai M">M Imai</name></author><author><name sortKey="Watanabe, T" uniqKey="Watanabe T">T Watanabe</name></author><author><name sortKey="Hatta, M" uniqKey="Hatta M">M Hatta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Herfst, S" uniqKey="Herfst S">S Herfst</name></author><author><name sortKey="Schrauwen, Ej" uniqKey="Schrauwen E">EJ Schrauwen</name></author><author><name sortKey="Linster, M" uniqKey="Linster M">M Linster</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Lm" uniqKey="Chen L">LM Chen</name></author><author><name sortKey="Blixt, O" uniqKey="Blixt O">O Blixt</name></author><author><name sortKey="Stevens, J" uniqKey="Stevens J">J Stevens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y Shi</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X Lu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tharakaraman, K" uniqKey="Tharakaraman K">K Tharakaraman</name></author><author><name sortKey="Raman, R" uniqKey="Raman R">R Raman</name></author><author><name sortKey="Viswanathan, K" uniqKey="Viswanathan K">K Viswanathan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tzarum, N" uniqKey="Tzarum N">N Tzarum</name></author><author><name sortKey="De Vries, Rp" uniqKey="De Vries R">RP de Vries</name></author><author><name sortKey="Zhu, X" uniqKey="Zhu X">X Zhu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name></author><author><name sortKey="Qi, J" uniqKey="Qi J">J Qi</name></author><author><name sortKey="Bi, Y" uniqKey="Bi Y">Y Bi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nailwal, H" uniqKey="Nailwal H">H Nailwal</name></author><author><name sortKey="Kamra, K" uniqKey="Kamra K">K Kamra</name></author><author><name sortKey="Lal, Sk" uniqKey="Lal S">SK. Lal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Belser, Ja" uniqKey="Belser J">JA Belser</name></author><author><name sortKey="Creager, Hm" uniqKey="Creager H">HM Creager</name></author><author><name sortKey="Sun, X" uniqKey="Sun X">X Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q Zhang</name></author><author><name sortKey="Shi, J" uniqKey="Shi J">J Shi</name></author><author><name sortKey="Deng, G" uniqKey="Deng G">G Deng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, R" uniqKey="Xu R">R Xu</name></author><author><name sortKey="De Vries, Rp" uniqKey="De Vries R">RP de Vries</name></author><author><name sortKey="Zhu, X" uniqKey="Zhu X">X Zhu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y Shi</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author><author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Martin, Sr" uniqKey="Martin S">SR Martin</name></author><author><name sortKey="Haire, Lf" uniqKey="Haire L">LF Haire</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wan, H" uniqKey="Wan H">H Wan</name></author><author><name sortKey="Perez, Dr" uniqKey="Perez D">DR. Perez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, X" uniqKey="Li X">X Li</name></author><author><name sortKey="Shi, J" uniqKey="Shi J">J Shi</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sorrell, Em" uniqKey="Sorrell E">EM Sorrell</name></author><author><name sortKey="Wan, H" uniqKey="Wan H">H Wan</name></author><author><name sortKey="Araya, Y" uniqKey="Araya Y">Y Araya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teng, Q" uniqKey="Teng Q">Q Teng</name></author><author><name sortKey="Xu, D" uniqKey="Xu D">D Xu</name></author><author><name sortKey="Shen, W" uniqKey="Shen W">W Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author><author><name sortKey="De Vries, Rp" uniqKey="De Vries R">RP de Vries</name></author><author><name sortKey="Tzarum, N" uniqKey="Tzarum N">N Tzarum</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tzarum, N" uniqKey="Tzarum N">N Tzarum</name></author><author><name sortKey="Mcbride, R" uniqKey="Mcbride R">R McBride</name></author><author><name sortKey="Nycholat, Cm" uniqKey="Nycholat C">CM Nycholat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ni, F" uniqKey="Ni F">F Ni</name></author><author><name sortKey="Kondrashkina, E" uniqKey="Kondrashkina E">E Kondrashkina</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vijaykrishna, D" uniqKey="Vijaykrishna D">D Vijaykrishna</name></author><author><name sortKey="Holmes, Ec" uniqKey="Holmes E">EC Holmes</name></author><author><name sortKey="Joseph, U" uniqKey="Joseph U">U Joseph</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ni, F" uniqKey="Ni F">F Ni</name></author><author><name sortKey="Mbawuike, In" uniqKey="Mbawuike I">IN Mbawuike</name></author><author><name sortKey="Kondrashkina, E" uniqKey="Kondrashkina E">E Kondrashkina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, M" uniqKey="Wang M">M Wang</name></author><author><name sortKey="Veit, M" uniqKey="Veit M">M. Veit</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Pologne</li></country></list><tree><country name="Pologne"><noRegion><name sortKey="Lazniewski, Michal" sort="Lazniewski, Michal" uniqKey="Lazniewski M" first="Michal" last="Lazniewski">Michal Lazniewski</name></noRegion><name sortKey="Dawson, Wayne K" sort="Dawson, Wayne K" uniqKey="Dawson W" first="Wayne K" last="Dawson">Wayne K. Dawson</name><name sortKey="Lazniewski, Michal" sort="Lazniewski, Michal" uniqKey="Lazniewski M" first="Michal" last="Lazniewski">Michal Lazniewski</name><name sortKey="Plewczynski, Dariusz" sort="Plewczynski, Dariusz" uniqKey="Plewczynski D" first="Dariusz" last="Plewczynski">Dariusz Plewczynski</name><name sortKey="Szczepi Ska, Teresa" sort="Szczepi Ska, Teresa" uniqKey="Szczepi Ska T" first="Teresa" last="Szczepi Ska">Teresa Szczepi Ska</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000260 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000260 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:6252403
|texte= The structural variability of the influenza A hemagglutinin receptor-binding site
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:29253080" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a H2N2V1
| This area was generated with Dilib version V0.6.33. |  |